Brand NamesCymbalta, Yentreve.
What is Cymbalta
Cymbalta (duloxetine) is an antidepressant in a group of drugs called selective serotonin and norepinephrine reuptake inhibitors (SSNRIs). Antidepressant medications are used to treat a variety of conditions, including depression and other mental/mood disorders. These medications can help prevent suicidal thoughts/attempts and provide other important benefits.
Cymbalta is also used to treat a chronic pain disorder called fibromyalgia, treat pain caused by nerve damage in people with diabetes (diabetic neuropathy) and to treat chronic musculoskeletal pain, including discomfort from osteoarthritis and chronic lower back pain.
Side effects of Cymbalta
The most common side effects identified in patients taking Cymbalta included:
- Dry mouth
- Decreased appetite
- Increased sweating
The most serious side effect is:
- very stiff (rigid) muscles, high fever, sweating, confusion, fast or uneven heartbeats, tremors;
- easy bruising, unusual bleeding;
- painful or difficult urination;
- nausea, pain in your upper stomach, itching;
- feeling like you might pass out;
- agitation, hallucinations;
For the acute and maintenance treatment of major depressive disorder (MDD), as well as acute management of generalized anxiety disorder. Also used for the management of neuropathic pain associated with diabetic peripheral neuropathy, and fibromyalgia. It has been used in the management of moderate to severe stress urinary incontinence in women.
Do not have Cymbalta if you have: manic depression, history of suicide attempts or suicidal thoughts, a recent heart attack , heart disease ,diabetic gastro paresis ,high blood pressure (hypertension) or low blood pressure (hypotension) ,seizures or epilepsy ,glaucoma (a condition of the eyes) ,liver disease, including liver failure or cirrhosis ,kidney problems, including kidney failure (renal failure) ,a bladder problem ,any allergies.
Also, let your healthcare provider know if you:
- are pregnant or thinking of becoming pregnant.
- are breastfeeding.
- drink alcohol regularly.
Cymbalta comes in 40 mg, 30 mg, and 60 mg capsules.
|Initial Treatment||40 mg/day (given as 20 mg twice daily) to 60 mg/day (given either once daily or as 30 mg twice daily).|
|Generalized Anxiety Disorder||60 mg administered once daily ( start -30 mg)|
|Diabetic Peripheral Neuropathic Pain||60 mg administered once daily( start -30 mg)|
|Fibromyalgia||60 mg administered once daily ( start -30 mg)|