Glimepiride

Brand Names

Amaryl

What is Glimepiride

Glimepiride is a medicine that is used together with diet and exercise to treat type 2 diabetes. It lowers blood sugar by causing the pancreas to produce insulin and helping the body use insulin efficiently.


Side effects of Glimepiride

Side effects of Glimepiride may include:

  • dizziness, headache, tired feeling;
  • mild nausea, vomiting, stomach pain, diarrhea;
  • increased skin sensitivity to sunlight;
  • mild itching or skin rash.

But if you have any of these serious symptoms it is necessary to visit your doctor immediately:

  • severe skin rash, itching, redness or irritation;
  • pale skin, easy bruising or bleeding, fever, unusual weakness;
  • numbness or tingly feeling;
  • trouble breathing;
  • feeling like you might pass out;
  • dark urine, clay-colored stools;
  • upper stomach pain, low fever, jaundice (yellowing of the skin or eyes);
  • nausea, vomiting, loss of appetite, feeling restless or irritable, confusion, hallucinations, muscle pain or weakness or seizure.


Indication

Glimepiride is used together with diet and exercise to treat type 2 diabetes.


Precautions

Before using Glimepiride you should inform your doctor if you have:

  • heart disease;
  • liver or kidney disease;
  • an allergy to sulfa drugs;
  • an enzyme deficiency called glucose-6-phosphate dehydrogenase deficiency (G6PD);
  • adrenal or pituitary gland problems;
  • if you are under-nourished.

Also tell your doctor if you are pregnant, trying to become pregnant or breastfeeding.


Dosage forms

The recommended dose is 1 mg or 2 mg once a day. If Glimepiride is taken in combination with insulin the dosage is 8 mg daily. The maximum recommended dose is 8 mg daily.