What is Neutrexin
Neutrexin is the brand name for trimetrexate glucuronate. Neutrexin is a medication that belongs to a class of a nonclassical folic acid inhibitors. Neutrexin is released as a sterile lyophilized powder that includes trimetrexate glucuronate equivalent to either 200mg or 25mg of trimetrexate without any preservatives or excipients. The powder is reconstituted prior to intravenous infusion.
Side effects of Neutrexin
Neutrexin can cause the following side effects:
Neutrexin is effective in the treatment of moderate to severe Pneumocystis carinii pneumonia (PCP) in patients with weak immune systems, including those with AIDS who are not able to take the standard treatment. Neutrexin is used together with leucovorin.
Neutrexin is an anti-infective agent. It acts by inhibiting DNA, RNA and protein synthesis, that leads to cell death.
You should not take this medication if:
- you are allergic to any ingredient in Neutrexin, leucovorin or methotrexate
- you are taking a nonsteroidal anti-inflammatory drug (NSAID) (eg, ibuprofen) or pristinamycin
- you are pregnant, planning to become pregnant or are breast-feeding
- you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
- you have allergies to medicines, foods or other substances
- you have bone marrow depression, a blood disorder or kidney or liver problems
The treatment plan and dose should be directed by the doctor. You should follow the instructions on the package. Neutrexin is commonly given as an injection at clinic.