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Sertraline hydrochloride

Brand Names

Sertraline hydrochloride

What is Sertraline hydrochloride

Sertraline hydrochloride (Zoloft) is a prescription antidepressant that related to a group of drugs called selective serotonin reuptake inhibitors (SSRIs). Sertraline is characterized by affecting chemicals in the brain that may become unbalanced and cause depression, panic, anxiety or obsessive-compulsive symptoms.


Side effects of Sertraline hydrochloride

Sertraline may cause the following side effects:

  • nausea
  • diarrhea
  • constipation
  • vomiting
  • dry mouth
  • gas or bloating
  • loss of appetite
  • weight changes
  • drowsiness
  • dizziness
  • excessive tiredness
  • headache
  • pain, burning, or tingling in the hands or feet
  • nervousness
  • uncontrollable shaking of a part of the body
  • sore throat
  • changes in sex drive or ability
  • excessive sweating

Once you have noticed any of these side effects, you should stop taking this medicine and contact your doctor as soon as possible:

  • blurred vision
  • seizures
  • fever, sweating, confusion, fast or irregular heartbeat, and severe muscle stiffness
  • abnormal bleeding or bruising
  • hallucinating (seeing things or hearing voices that do not exist)


Indication

Sertraline is used to treat a number of such conditions as:

  • Depression (also known as major depression or clinical depression)
  • Obsessive-compulsive disorder (OCD)
  • Panic disorder
  • Post-traumatic stress disorder (PTSD)
  • Premenstrual dysphoric disorder (PMDD)
  • Social anxiety disorder (social phobia)


Precautions

It is necessary to inform your doctor if you have:

  • Bipolar disorder or a family history of bipolar disorder (also known asmanic depression)
  • A history of suicide attempts or suicidal thoughts
  • Diabetes
  • Seizures or epilepsy
  • Liver disease, including liver failure or cirrhosis
  • Had a recent heart attack (or if you have unstable heart disease)
  • Any allergies, including allergies to food, dyes, preservatives or latex
  • Are pregnant, want to be pregnant or breastfeeding


Dosage forms

Sertraline dose for Depression or Obsessive-Compulsive Disorder (OCD)

For people suffering from depression or obsessive-compulsive disorder (OCD), the recommended starting dose is sertraline 50 mg once a day. Your doctor may increase the sertraline dose if symptoms continue or decrease the dose if side effects occur.

Sertraline dose for Panic Disorder, Post-traumatic Stress Disorder or Social Anxiety Disorder

For people with panic disorder, post-traumatic stress disorder (PTSD) or social anxiety disorder, the recommended dose is sertraline 25 mg once a day. After a week, your doctor may increase the dose up to 50 mg of sertraline once a day. Your doctor may also increase the sertraline dose if symptoms continue or decrease the dose if side effects occur.