Show me the shape of your body and I will tell you what diseases you will have!
Genetics influences the shape of your body and which shape can lead to the disease. You may have an "apple" or a "pear" body shape.
If your figure is in the shape of an apple or pear, it means that the exact cause of it your genetic variants. A new research concerning the common genetic variants with propensity towards apple- and pear- body shapes was made by the scientists recently. According to this research the scientists found out how genetics influences the size of waist and hip in nearly 200,000 people.
The research identified 14 single nucleotide polymorphisms (SNPs or common genetic variants) - 13 new and only one associated with body fat distribution. Thus "apples" whose weight concentrates around their middles have a greater risk for development of heart disease and type 2 diabetes than "pears".
Moreover the researches showed that genetics play a more significant role in determining body fat distribution in women than in men.
Together with obesity and many other conditions with a strong environmental component, genes are only the smallest part of causes of variability in body fat distribution.
The scientists made an interesting observation: the variants associated with body fat distribution are different from those variants associated with overall body fat content. The location of body fat plays an important role to have a risk of getting disease and a better understanding of these genetic risk factors underlying increased the size of waist and hip may lead to improved therapies or lifestyle recommendations.
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